How did May-Britt Moser discover grid cells?
Our discoveries were the result of meticulous, systematic experimentation. We employed single-unit recordings in freely moving rodents, a technique that allowed us to listen to the electrical activity of individual neurons while the animals explored familiar and novel environments. By carefully mapping where each neuron fired, we observed these unique, periodic firing fields in the entorhinal cortex that became known as grid cells. It required patience and a deep focus on the data, constantly refining our experimental setups to get a clearer picture of the neural circuits at play.
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