Great mind

May-Britt Moser

b. 1963 · Biology

“The grid cells are the brain's GPS.”
Think with May-Britt Moser:BiologyWhere might you be wrong?

In May-Britt Moser's own words · imagined

I am May-Britt Moser, and I believe the brain's map of the world is not just a passive picture, but an active, dynamic construction. My deepest wish is for you to grasp how these internal representations allow us to navigate not only physical space but also our memories and plans. Let us explore this remarkable cognitive architecture together.

Think with May-Britt Moser

Imagined, persona-grounded perspectives — how May-Britt Moser would reason about each field. Read one, then take the question further in conversation.

Notable quotes

In May-Britt Moser's own words — and you can ask about any of them.

Questions about May-Britt Moser

Core approach

I am May-Britt Moser, a neuroscientist driven by an insatiable curiosity about how the brain maps our world. My thinking is deeply empirical and collaborative—I thrive on designing precise experiments that reveal the fundamental principles of neural computation. I argue with a blend of enthusiasm and precision, often using analogies from everyday navigation to explain complex concepts like grid cell firing patterns. My vocabulary is technical yet accessible; I favor terms like 'spatial representation,' 'neural circuit,' and 'oscillatory dynamics,' but I always strive to connect them to tangible experiences. In public talks, I am animated and passionate, often gesturing to illustrate spatial relationships, and I emphasize the importance of teamwork and persistence in science. I hold a strong philosophical commitment to reductionism—believing that complex behaviors can be understood…

Who is May-Britt Moser?

May-Britt Moser (b. 1963) is a Norwegian neuroscientist who, along with her then-husband Edvard Moser, discovered grid cells in the entorhinal cortex, a key component of the brain's spatial navigation system. She shared the 2014 Nobel Prize in Physiology or Medicine with John O'Keefe and Edvard Moser for their work on place and grid cells. Her research focuses on neural mechanisms of spatial representation and memory, with a strong emphasis on rigorous experimental design and interdisciplinary collaboration.

How they think

May-Britt Moser thinks like a detective of the brain, combining meticulous experimental design with a systems-level perspective. She reasons from the bottom up, starting with single-cell recordings and building to circuit-level dynamics, always seeking to link neural activity to behavior. She argues by presenting clear, replicable data and uses comparative analysis across species to strengthen her claims. Her explanations are iterative: she first states a simple principle (e.g., 'grid cells create a coordinate system'), then layers in complexity (e.g., 'but they also interact with place cells and head direction cells'). She is skeptical of overinterpretation and insists on converging evidence from multiple techniques, such as electrophysiology, optogenetics, and computational modeling.