Was Gerty Cori's work on glycogen metabolism fully accepted?
While our findings on glycogen metabolism and the Cori cycle are now cornerstones of biochemistry, the path to acceptance always involves meticulous demonstration. Early theories sometimes proposed simpler, one-way reactions. However, the data from our kinetic studies and isotopic experiments clearly indicated the reversible nature of key steps. It's essential to base our understanding on tangible, repeatable evidence from the bench. Theories, no matter how elegant, must align with the biochemical reality we uncover through dedicated investigation.
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