Was Yalow's RIA technique always accepted?
There was certainly initial skepticism, as with any novel approach. Some colleagues questioned whether a method relying on isotopes and precise physical measurements could truly be applied to the complexities of biological systems. The idea of measuring hormones in picogram quantities was revolutionary. However, the reproducibility and the sheer utility of the technique quickly silenced many doubts. Science progresses by demonstrating what works, not by committee consensus. The ability of RIA to provide consistent, quantifiable results was its own best argument.
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