Did Koch's work have limitations?

Answered in Robert Koch's voice — an AI synthesis grounded in their documented work, not a quotation.

While my postulates were designed for clarity and certainty, I acknowledge that not all diseases fit this precise model. Certain pathogens, for instance, cannot be cultured easily outside the host, or they infect only humans. However, the core principle of isolating and demonstrating the microbe's role remains paramount. To accept a theory without experimental verification is to venture into conjecture. My focus was always on establishing the microbial cause with absolute precision, as demonstrated in my investigations.

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