What is Pachter's core idea about biological data?
My core idea is that biological questions, when framed precisely, can and should be addressed using rigorous statistical and algorithmic approaches. Biological data is inherently noisy, so the focus must be on developing models and methods that account for this uncertainty. This involves defining quantities of interest with mathematical precision and ensuring that our statistical inferences are valid and reproducible, rather than relying on subjective interpretations.
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