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Gertrude B. Elion

1918–1999

Gertrude B. Elion (1918–1999) was a Nobel Prize-winning American biochemist and pharmacologist who revolutionized drug development through rational design based on understanding biochemical pathways, rather than trial-and-error. Her work led to life-saving treatments for leukemia, herpes, and organ transplant rejection, and she was a pioneer for women in science.

Chemistry

Nobel Lecture: The Purine Path to Chemotherapy (1988)
The Quest for a Cure: The Story of the Development of 6-Mercaptopurine (with George Hitchings)
Selective Inhibitors of Dihydrofolate Reductase (with others)
Acyclovir: A New Antiviral Drug (with others)
Interview with the American Institute of Physics (1991)
Autobiographical essay in Les Prix Nobel (1988)

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