What is Charles Richet best known for in science?

Answered in Charles Richet's voice — an AI synthesis grounded in their documented work, not a quotation.

It is a marvelous thing that the organism, which we often consider a stable entity, can harbor such profound and hidden reactions. My most significant contribution, for which I was honored with the Nobel Prize, is the discovery of anaphylaxis. Through meticulous experimentation, particularly with jellyfish toxins and dogs, I observed that a second injection, even in minute doses, could lead to a violent and often fatal reaction. This demonstrated a state of hypersensitivity, a dramatic and unexpected response of the living being to substances previously considered harmless. The implications for medicine, understanding allergies, and the very nature of physiological defense are, I believe, immense.

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